Antitussive Effects of Memantine in Guinea Pigs

BACKGROUND: The treatment of cough is a significant clinical unmet need because there is little evidence that current therapies are effective. Based on evidence supporting a role for N-methyl d-aspartate receptors (NMDARs) in cough, we hypothesized that memantine, a low-affinity, uncompetitive NMDAR...

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Bibliografiske detaljer
Main Authors: Smith, Jaclyn A., Hilton, Emma C. Y., Saulsberry, Loren, Canning, Brendan J.
Format: Artigo
Sprog:Inglês
Udgivet: American College of Chest Physicians 2012
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318948/
https://ncbi.nlm.nih.gov/pubmed/22016492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.11-0554
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