TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) depends on the initial activation of CD4(+) T cells responsive to myelin autoantigens. The key antigen presenting cell (APC) population that drives the activation of naïve T cells most efficiently is the dendritic cell (DC). As such, we sho...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mellanby, Richard J, Cambrook, Helen, Turner, Darryl G, O’Connor, Richard A, Leech, Melanie D, Kurschus, Florian C, MacDonald, Andrew S, Arnold, Bernd, Anderton, Stephen M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2012
Aiheet:
Short Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520704/
https://ncbi.nlm.nih.gov/pubmed/23111144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-248
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia