Dual roles of PARP-1 promote cancer growth and progression

Poly(ADP-ribose) polymerase-1 (PARP-1) is an abundant nuclear enzyme that modifies substrates by poly(ADP-ribose)-ylation. PARP-1 has well-described functions in DNA damage repair, and also functions as a context-specific regulator of transcription factors. Using multiple models, data demonstrate th...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Schiewer, Matthew J., Goodwin, Jonathan F., Han, Sumin, Brenner, J. Chad, Augello, Michael A., Dean, Jeffry L., Liu, Fengzhi, Planck, Jamie L., Ravindranathan, Preethi, Chinnaiyan, Arul M., McCue, Peter, Gomella, Leonard G., Raj, Ganesh V., Dicker, Adam P., Brody, Jonathan R., Pascal, John M., Centenera, Margaret M., Butler, Lisa M., Tilley, Wayne D., Feng, Felix Y., Knudsen, Karen E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519969/
https://ncbi.nlm.nih.gov/pubmed/22993403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0120
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk