Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA)

BACKGROUND: Tuberculosis (TB) still remains one of the most deadly infectious diseases in the world. Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA) is a member of the fatty acid elongation system type II, providing precursors of mycolic acids that are essential to the bacterial cell grow...

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Bibliographic Details
Main Authors: Rosado, Leonardo A, Caceres, Rafael Andrade, de Azevedo, Walter Filgueira, Basso, Luiz A, Santos, Diógenes S
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519566/
https://ncbi.nlm.nih.gov/pubmed/23006410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-526
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