The Mode of Action of Recombinant Mycobacterium tuberculosis Shikimate Kinase: Kinetics and Thermodynamics Analyses

Tuberculosis remains as one of the main cause of mortality worldwide due to a single infectious agent, Mycobacterium tuberculosis. The aroK-encoded M. tuberculosis Shikimate Kinase (MtSK), shown to be essential for survival of bacilli, catalyzes the phosphoryl transfer from ATP to the carbon-3 hydro...

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Bibliografiske detaljer
Main Authors: Rosado, Leonardo Astolfi, Vasconcelos, Igor Bordin, Palma, Mário Sérgio, Frappier, Vincent, Najmanovich, Rafael Josef, Santos, Diógenes Santiago, Basso, Luiz Augusto
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646032/
https://ncbi.nlm.nih.gov/pubmed/23671579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061918
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