Biochemical Characterization of Uracil Phosphoribosyltransferase from Mycobacterium tuberculosis

Uracil phosphoribosyltransferase (UPRT) catalyzes the conversion of uracil and 5-phosphoribosyl-α-1-pyrophosphate (PRPP) to uridine 5′-monophosphate (UMP) and pyrophosphate (PP(i)). UPRT plays an important role in the pyrimidine salvage pathway since UMP is a common precursor of all pyrimidine nucle...

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Main Authors: Villela, Anne Drumond, Ducati, Rodrigo Gay, Rosado, Leonardo Astolfi, Bloch, Carlos Junior, Prates, Maura Vianna, Gonçalves, Danieli Cristina, Ramos, Carlos Henrique Inacio, Basso, Luiz Augusto, Santos, Diogenes Santiago
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570474/
https://ncbi.nlm.nih.gov/pubmed/23424660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056445
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