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Substrate Recognition by β-Ketoacyl-ACP Synthases()

β-Ketoacyl-ACP synthase (KAS) enzymes catalyze Claisen condensation reactions in the fatty acid biosynthesis pathway. These reactions follow a ping-pong mechanism in which a donor substrate acylates the active site cysteine residue after which the acyl group is condensed with the malonyl-ACP accepto...

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Detalhes bibliográficos
Main Authors: Borgaro, Janine G., Chang, Andrew, Machutta, Carl A., Zhang, Xujie, Tonge, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361727/
https://ncbi.nlm.nih.gov/pubmed/22017312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201199x
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