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Substrate Recognition by the Human Fatty-acid Synthase
The human fatty-acid synthase (HFAS) is a potential target for anti-tumor drug discovery. As a prelude to the design of compounds that target the enoyl reductase (ER) component of HFAS, the recognition of NADPH and exogenous substrates by the ER active site has been investigated. Previous studies de...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442872/ https://ncbi.nlm.nih.gov/pubmed/16215233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M507082200 |
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