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Role of Galectin-3 in Classical and Alternative Macrophage Activation in the Liver following Acetaminophen Intoxication()

Inflammatory macrophages have been implicated in hepatotoxicity induced by the analgesic, acetaminophen (APAP). In these studies we characterized the phenotype of macrophages accumulating in the liver following APAP intoxication and evaluated the role of galectin-3 (Gal-3) in macrophage activation....

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Autores principales: Dragomir, Ana-Cristina Docan, Sun, Richard, Choi, Hyejeong, Laskin, Jeffrey D., Laskin, Debra L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518653/
https://ncbi.nlm.nih.gov/pubmed/23175698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201851
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