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Role of Galectin-3 in Classical and Alternative Macrophage Activation in the Liver following Acetaminophen Intoxication()

Inflammatory macrophages have been implicated in hepatotoxicity induced by the analgesic, acetaminophen (APAP). In these studies we characterized the phenotype of macrophages accumulating in the liver following APAP intoxication and evaluated the role of galectin-3 (Gal-3) in macrophage activation....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dragomir, Ana-Cristina Docan, Sun, Richard, Choi, Hyejeong, Laskin, Jeffrey D., Laskin, Debra L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518653/
https://ncbi.nlm.nih.gov/pubmed/23175698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201851
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