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Role of Galectin-3 in Classical and Alternative Macrophage Activation in the Liver following Acetaminophen Intoxication()

Inflammatory macrophages have been implicated in hepatotoxicity induced by the analgesic, acetaminophen (APAP). In these studies we characterized the phenotype of macrophages accumulating in the liver following APAP intoxication and evaluated the role of galectin-3 (Gal-3) in macrophage activation....

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Detalhes bibliográficos
Main Authors: Dragomir, Ana-Cristina Docan, Sun, Richard, Choi, Hyejeong, Laskin, Jeffrey D., Laskin, Debra L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518653/
https://ncbi.nlm.nih.gov/pubmed/23175698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201851
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