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Role of Galectin-3 in Acetaminophen-Induced Hepatotoxicity and Inflammatory Mediator Production

Galectin-3 (Gal-3) is a β-galactoside-binding lectin implicated in the regulation of macrophage activation and inflammatory mediator production. In the present studies, we analyzed the role of Gal-3 in liver inflammation and injury induced by acetaminophen (APAP). Treatment of wild-type (WT) mice wi...

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Detalhes bibliográficos
Main Authors: Dragomir, Ana-Cristina, Sun, Richard, Mishin, Vladimir, Hall, LeRoy B., Laskin, Jeffrey D., Laskin, Debra L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355315/
https://ncbi.nlm.nih.gov/pubmed/22461450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs117
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