Potential Role of Caveolin-1 in Acetaminophen-Induced Hepatotoxicity

Caveolin-1 (Cav-1) is a membrane scaffolding protein which functions to regulate intracellular compartmentalization of various signaling molecules. In the present studies, transgenic mice with a targeted disruption of the Cav-1 gene (Cav-1(−/−)) were used to assess the role of Cav-1 in acetaminophen...

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Main Authors: Gardner, Carol R., Gray, Joshua P., Joseph, Laurie B., Cervelli, Jessica, Bremer, Nicole, Kim, Yunjung, Mishin, Vladimir, Laskin, Jeffrey D., Laskin, Debra L.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862893/
https://ncbi.nlm.nih.gov/pubmed/20100502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.01.008
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