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Intratumoral TNFα improves immunotherapy
Solid tumors are frequently resistant to immunotherapy. We demonstrated that low-dose tumor necrosis factorα (TNFα), when directly targeted to the tumor environment, exerts dual effects by improving vessel functionality and activating immune cells. This vascular remodeling in an inflammatory context...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518514/ https://ncbi.nlm.nih.gov/pubmed/23243605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20981 |
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