Učitavanje...
Tumor-targeted TNFα stabilizes tumor vessels and enhances active immunotherapy
Solid tumors are intrinsically resistant to immune rejection. Abnormal tumor vasculature can act as a barrier for immune cell migration into tumors. We tested whether targeting IFNγ and/or TNFα into pancreatic neuroendocrine tumors can alleviate immune suppression. We found that intratumoral IFNγ ca...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356673/ https://ncbi.nlm.nih.gov/pubmed/22547817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118296109 |
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