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Shock block for improved immunotherapy

Cancer cells use heat shock proteins (HSP) to stabilize growth/survival-associated client proteins such as receptor tyrosine kinases (RTKs), in vivo. Our recent work suggests that chemical HSP90 inhibitors combined with a vaccination strategy targeting HSP90 client proteins that are (over)expressed...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rao, Aparna, Lowe, Devin B., Storkus, Walter J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518526/
https://ncbi.nlm.nih.gov/pubmed/23243617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21174
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