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Combined vaccine + axitinib therapy yields superior anti-tumor efficacy in a murine melanoma model

Axitinib, a tyrosine kinase inhibitor (TKI) of vascular endothelial growth factor receptors has demonstrated modest efficacy when applied as a single agent in the setting of advanced-stage melanoma. Based on the reported ability of axitinib to “normalize” the tumor vasculature, we hypothesize that c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bose, Anamika, Lowe, Devin B., Rao, Aparna, Storkus, Walter J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340498/
https://ncbi.nlm.nih.gov/pubmed/22504156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0b013e3283538293
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