Vav3 Enhances Androgen Receptor Splice Variant Activity and Is Critical for Castration-Resistant Prostate Cancer Growth and Survival

Advanced or metastatic prostate cancer is treated by androgen deprivation; however, patients inevitably relapse with castration-resistant prostate cancer (CRPC). CRPC remains dependent on androgen receptor (AR) signaling, which may include constitutive, ligand-independent action of naturally occurri...

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Autores principales: Peacock, Stephanie O., Fahrenholtz, Cale D., Burnstein, Kerry L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2012
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517715/
https://ncbi.nlm.nih.gov/pubmed/23023561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1165
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