Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival

BACKGROUND: Constitutively active androgen receptor variants (AR-V) lacking the ligand binding domain (LBD) may promote the development of castration-resistant prostate cancer (CRPC). The expression of AR-Vs in the clinically most important metastatic site, the bone, has, however, not been well docu...

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Detalhes bibliográficos
Main Authors: Hörnberg, Emma, Ylitalo, Erik Bovinder, Crnalic, Sead, Antti, Henrik, Stattin, Pär, Widmark, Anders, Bergh, Anders, Wikström, Pernilla
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084247/
https://ncbi.nlm.nih.gov/pubmed/21552559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019059
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