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Novel Interaction between the Co-chaperone Cdc37 and Rho GTPase Exchange Factor Vav3 Promotes Androgen Receptor Activity and Prostate Cancer Growth

Elevated androgen receptor (AR) activity in castration-resistant prostate cancer may occur through increased levels of AR co-activator proteins. Vav3, a guanine nucleotide exchange factor, is up-regulated following progression to castration resistance in preclinical models and is overexpressed in a...

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Библиографические подробности
Главные авторы: Wu, Fayi, Peacock, Stephanie O., Rao, Shuyun, Lemmon, Sandra K., Burnstein, Kerry L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581368/
https://ncbi.nlm.nih.gov/pubmed/23281476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390963
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