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Fast, Cell-compatible Click Chemistry with Copper-chelating Azides for Biomolecular Labeling
[Image: see text] We report that azides capable of copper-chelation undergo much faster “Click chemistry” (copper-accelerated azide-alkyne cycloaddition, or CuAAC) than nonchelating azides under a variety of biocompatible conditions. This kinetic enhancement allowed us to perform site-specific prote...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517120/ https://ncbi.nlm.nih.gov/pubmed/22555882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201108181 |
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