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Raltegravir: molecular basis of its mechanism of action

Integration of the HIV-1 viral DNA generated by reverse transcription of the RNA genome into the host cell chromosomes is a key step of viral replication, catalyzed by the viral integrase. In October 2007, the first integrase inhibitor, raltegravir, was approved for clinical use under the name of Is...

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Podrobná bibliografie
Hlavní autoři: Mouscadet, Jean-François, Tchertanov, Luba
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516820/
https://ncbi.nlm.nih.gov/pubmed/19959411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-783X-14-S3-5
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