The Tim3–Galectin 9 Pathway Induces Antibacterial Activity in Human Macrophages Infected with Mycobacterium tuberculosis

T cell Ig and mucin domain 3 (Tim3) is an inhibitory molecule involved in immune tolerance, autoimmune responses, and antiviral immune evasion. However, we recently demonstrated that Tim3 and Galectin-9 (Gal9) interaction induces a program of macrophage activation that results in killing of Mycobact...

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Bibliografski detalji
Glavni autori: Sada-Ovalle, Isabel, Chávez-Galán, Leslie, Torre-Bouscoulet, Luis, Nava-Gamiño, Lourdes, Barrera, Lourdes, Jayaraman, Pushpa, Torres-Rojas, Martha, Salazar-Lezama, Miguel Angel, Behar, Samuel M.
Format: Artigo
Jezik:Inglês
Izdano: AAI 2012
Teme:
Host Defense
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516679/
https://ncbi.nlm.nih.gov/pubmed/23180819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200990
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