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Lipoarabinomannan Decreases Galectin-9 Expression and Tumor Necrosis Factor Pathway in Macrophages Favoring Mycobacterium tuberculosis Intracellular Growth

Lipoarabinomannan (LAM) is a lipid virulent factor secreted by Mycobacterium tuberculosis (Mtb). LAM can be found in the sputum and urine of patients with active tuberculosis. When human monocytes are differentiated into macrophages [monocyte-derived macrophages (MDM)] in the presence of LAM, MDM ar...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chávez-Galán, Leslie, Ramon-Luing, Lucero, Carranza, Claudia, Garcia, Irene, Sada-Ovalle, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711832/
https://ncbi.nlm.nih.gov/pubmed/29230224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01659
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