Pre-Exposure of Mycobacterium tuberculosis-Infected Macrophages to Crystalline Silica Impairs Control of Bacterial Growth by Deregulating the Balance between Apoptosis and Necrosis

Inhalation of crystalline silica (CS) particles increases the risk of pulmonary tuberculosis; however, the precise mechanism through which CS exposure facilitates Mycobacterium tuberculosis (Mtb) infection is unclear. We speculate that macrophage exposure to CS deregulates the cell death pathways th...

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Detalhes bibliográficos
Main Authors: Chávez-Galán, Leslie, Ramon-Luing, Lucero A., Torre-Bouscoulet, Luis, Pérez-Padilla, Rogelio, Sada-Ovalle, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838437/
https://ncbi.nlm.nih.gov/pubmed/24278357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080971
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