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TIM-3 Regulates Distinct Functions in Macrophages

The transmembrane protein TIM-3 is a type I protein expressed by sub-types of lymphoid cells, such as lymphocytes Th1, Th17, Tc1, NK, as well as in myeloid cells. Scientific evidence indicates that this molecule acts as a negative regulator of T lymphocyte activation and that its expression is modif...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ocaña-Guzman, Ranferi, Torre-Bouscoulet, Luis, Sada-Ovalle, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904032/
https://ncbi.nlm.nih.gov/pubmed/27379093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00229
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