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UGT1A1 predicts outcome in colorectal cancer treated with irinotecan and fluorouracil
AIM: To evaluate effects of UDP-glucuronosyltransferase1A1 (UGT1A1) and thymidylate synthetase (TS) gene polymorphisms on irinotecan in metastatic colorectal cancer (mCRC). METHODS: Two irinotecan- and fluorouracil-based regimens, FOLFIRI and IFL, were selected as second-line therapy for 138 Chinese...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Co., Limited
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516223/ https://ncbi.nlm.nih.gov/pubmed/23236239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i45.6635 |
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