UGT1A1 gene polymorphism: Impact on toxicity and efficacy of irinotecan-based regimens in metastatic colorectal cancer

AIM: To investigate the correlation between uridine diphosphate glucuronosyl transferase 1A1 (UGT1A1) gene polymorphisms and irinotecan-associated side effects and parameters of drug efficacy in patients with metastatic colorectal cancer (mCRC) receiving a low-dose weekly irinotecan chemotherapeutic...

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Main Authors: Schulz, Christoph, Heinemann, Volker, Schalhorn, Andreas, Moosmann, Nikolas, Zwingers, Thomas, Boeck, Stefan, Giessen, Clemens, Stemmler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2009
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Brief Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768885/
https://ncbi.nlm.nih.gov/pubmed/19859999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.5058
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