Epithelial–mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib

Although cyclooxygenase-2 (COX-2) inhibitors, such as the late stage development drug apricoxib, exhibit antitumor activity, their mechanisms of action have not been fully defined. In this study, we characterized the mechanisms of action of apricoxib in HT29 colorectal carcinoma. Apricoxib was weakl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kirane, Amanda, Toombs, Jason E, Larsen, Jill E, Ostapoff, Katherine T, Meshaw, Kathryn R, Zaknoen, Sara, Brekken, Rolf A, Burrows, Francis J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Original Manuscript
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514897/
https://ncbi.nlm.nih.gov/pubmed/22678114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs195
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