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Intermediate state trapping of a voltage sensor
Voltage sensor domains (VSDs) regulate ion channels and enzymes by undergoing conformational changes depending on membrane electrical signals. The molecular mechanisms underlying the VSD transitions are not fully understood. Here, we show that some mutations of I241 in the S1 segment of the Shaker K...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514728/ https://ncbi.nlm.nih.gov/pubmed/23183699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210827 |
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