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Moving gating charges through the gating pore in a Kv channel voltage sensor

Voltage sensor domains (VSDs) regulate ion channels and enzymes by transporting electrically charged residues across a hydrophobic VSD constriction called the gating pore or hydrophobic plug. How the gating pore controls the gating charge movement presently remains debated. Here, using saturation mu...

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Hlavní autoři: Lacroix, Jérôme J., Hyde, H. Clark, Campos, Fabiana V., Bezanilla, Francisco
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024920/
https://ncbi.nlm.nih.gov/pubmed/24782544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406161111
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