PIP(2) controls voltage-sensor movement and pore opening of Kv channels through the S4–S5 linker

Voltage-gated K(+) (Kv) channels couple the movement of a voltage sensor to the channel gate(s) via a helical intracellular region, the S4–S5 linker. A number of studies link voltage sensitivity to interactions of S4 charges with membrane phospholipids in the outer leaflet of the bilayer. Although t...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Rodriguez-Menchaca, Aldo A., Adney, Scott K., Tang, Qiong-Yao, Meng, Xuan-Yu, Rosenhouse-Dantsker, Avia, Cui, Meng, Logothetis, Diomedes E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437867/
https://ncbi.nlm.nih.gov/pubmed/22891352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207901109
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk