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Cholesterol Sensitivity of KIR2.1 Is Controlled by a Belt of Residues around the Cytosolic Pore

Kir channels play an important role in setting the resting membrane potential and modulating membrane excitability. A common feature of several Kir channels is that they are regulated by cholesterol. Yet, the mechanism by which cholesterol affects channel function is unclear. We recently showed that...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Rosenhouse-Dantsker, Avia, Logothetis, Diomedes E., Levitan, Irena
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Biophysical Society 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021658/
https://ncbi.nlm.nih.gov/pubmed/21244834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.086
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