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Cholesterol Sensitivity of KIR2.1 Is Controlled by a Belt of Residues around the Cytosolic Pore
Kir channels play an important role in setting the resting membrane potential and modulating membrane excitability. A common feature of several Kir channels is that they are regulated by cholesterol. Yet, the mechanism by which cholesterol affects channel function is unclear. We recently showed that...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021658/ https://ncbi.nlm.nih.gov/pubmed/21244834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.086 |
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