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Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding

Inwardly rectifying potassium (Kir) channels were the first shown to be directly activated by phosphoinositides in general and phosphatidylinositol bisphosphate (PIP(2)) in particular. Atomic resolution structures have been determined for several mammalian and bacterial Kir channels. Basic residues,...

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Detalhes bibliográficos
Main Authors: Logothetis, Diomedes E, Lupyan, Dmitry, Rosenhouse-Dantsker, Avia
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075264/
https://ncbi.nlm.nih.gov/pubmed/17495041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.133157
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