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Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding

Inwardly rectifying potassium (Kir) channels were the first shown to be directly activated by phosphoinositides in general and phosphatidylinositol bisphosphate (PIP(2)) in particular. Atomic resolution structures have been determined for several mammalian and bacterial Kir channels. Basic residues,...

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Bibliografiske detaljer
Main Authors: Logothetis, Diomedes E, Lupyan, Dmitry, Rosenhouse-Dantsker, Avia
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075264/
https://ncbi.nlm.nih.gov/pubmed/17495041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.133157
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