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Cholesterol sensitivity of KIR2.1 depends on functional inter-links between the N and C termini

In recent years, cholesterol has been emerging as a major regulator of ion channel function. We have previously shown that cholesterol suppresses Kir2 channels, a subfamily of constitutively active strongly rectifying K(+) channels. Furthermore, our earlier studies have shown that cholesterol sensit...

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Autores principales: Rosenhouse-Dantsker, Avia, Noskov, Sergei, Logothetis, Diomedes E, Levitan, Irena
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989358/
https://ncbi.nlm.nih.gov/pubmed/23807091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.25437
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