Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2

We have shown earlier that Kir2 channels are suppressed by the elevation of membrane cholesterol. Moreover, it is also well known that activation of Kir channels is critically dependent on a regulatory phospholipid, phosphatidylinositol-4,5-bisphosphate (PIP2). In this study we examined the cross-ta...

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Bibliografiske detaljer
Udgivet i:Comput Struct Biotechnol J
Main Authors: Rosenhouse-Dantsker, Avia, Epshtein, Yulia, Levitan, Irena
Format: Artigo
Sprog:Inglês
Udgivet: Research Network of Computational and Structural Biotechnology 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232564/
https://ncbi.nlm.nih.gov/pubmed/25408847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2014.09.007
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