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Direct Regulation of Prokaryotic Kir Channel by Cholesterol

Our earlier studies have shown that channel activity of Kir2 subfamily of inward rectifiers is strongly suppressed by the elevation of cellular cholesterol. The goal of this study is to determine whether cholesterol suppresses Kir channels directly. To achieve this goal, purified prokaryotic Kir (Ki...

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Detalhes bibliográficos
Main Authors: Singh, Dev K., Rosenhouse-Dantsker, Avia, Nichols, Colin G., Enkvetchakul, Decha, Levitan, Irena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781626/
https://ncbi.nlm.nih.gov/pubmed/19740741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011221
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