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Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2

We have shown earlier that Kir2 channels are suppressed by the elevation of membrane cholesterol. Moreover, it is also well known that activation of Kir channels is critically dependent on a regulatory phospholipid, phosphatidylinositol-4,5-bisphosphate (PIP2). In this study we examined the cross-ta...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Main Authors: Rosenhouse-Dantsker, Avia, Epshtein, Yulia, Levitan, Irena
Formato: Artigo
Idioma:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232564/
https://ncbi.nlm.nih.gov/pubmed/25408847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2014.09.007
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