Structural basis for gating charge movement in the voltage sensor of a sodium channel

Voltage-dependent gating of ion channels is essential for electrical signaling in excitable cells, but the structural basis for voltage sensor function is unknown. We constructed high-resolution structural models of resting, intermediate, and activated states of the voltage-sensing domain of the bac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yarov-Yarovoy, Vladimir, DeCaen, Paul G., Westenbroek, Ruth E., Pan, Chien-Yuan, Scheuer, Todd, Baker, David, Catterall, William A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258622/
https://ncbi.nlm.nih.gov/pubmed/22160714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118434109
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