Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events

Lung cancer is a highly heterogeneous disease in terms of both underlying genetic lesions and response to therapeutic treatments. We performed deep whole-genome sequencing and transcriptome sequencing on 19 lung cancer cell lines and three lung tumor/normal pairs. Overall, our data show that cell li...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Jinfeng, Lee, William, Jiang, Zhaoshi, Chen, Zhongqiang, Jhunjhunwala, Suchit, Haverty, Peter M., Gnad, Florian, Guan, Yinghui, Gilbert, Houston N., Stinson, Jeremy, Klijn, Christiaan, Guillory, Joseph, Bhatt, Deepali, Vartanian, Steffan, Walter, Kimberly, Chan, Jocelyn, Holcomb, Thomas, Dijkgraaf, Peter, Johnson, Stephanie, Koeman, Julie, Minna, John D., Gazdar, Adi F., Stern, Howard M., Hoeflich, Klaus P., Wu, Thomas D., Settleman, Jeff, de Sauvage, Frederic J., Gentleman, Robert C., Neve, Richard M., Stokoe, David, Modrusan, Zora, Seshagiri, Somasekar, Shames, David S., Zhang, Zemin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2012
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514662/
https://ncbi.nlm.nih.gov/pubmed/23033341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.140988.112
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