Recurrent R-spondin fusions in colon cancer

Identifying and understanding changes in cancer genomes is essential for the development of targeted therapeutics(1). Here we analyse systematically more than 70 pairs of primary human colon tumours by applying next-generation sequencing to characterize their exomes, transcriptomes and copy-number a...

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Autors principals: Seshagiri, Somasekar, Stawiski, Eric W., Durinck, Steffen, Modrusan, Zora, Storm, Elaine E., Conboy, Caitlin B., Chaudhuri, Subhra, Guan, Yinghui, Janakiraman, Vasantharajan, Jaiswal, Bijay S., Guillory, Joseph, Ha, Connie, Dijkgraaf, Gerrit J. P., Stinson, Jeremy, Gnad, Florian, Huntley, Melanie A., Degenhardt, Jeremiah D., Haverty, Peter M., Bourgon, Richard, Wang, Weiru, Koeppen, Hartmut, Gentleman, Robert, Starr, Timothy K., Zhang, Zemin, Largaespada, David A., Wu, Thomas D., de Sauvage, Frederic J
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690621/
https://ncbi.nlm.nih.gov/pubmed/22895193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11282
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