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Molecular Interactions of Alzheimer's Biomarker FDDNP with Aβ Peptide
All-atom explicit solvent model and replica exchange molecular dynamics were used to investigate binding of Alzheimer's biomarker FDDNP to the Aβ(10–40) monomer. At low and high concentrations, FDDNP binds with high affinity to two sites in the Aβ(10–40) monomer located near the central hydroph...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Biophysical Society
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514529/ https://ncbi.nlm.nih.gov/pubmed/23283233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.10.003 |
| Etiketak: |
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