Calcium Enhances Binding of Aβ Monomer to DMPC Lipid Bilayer

Using isobaric-isothermal replica-exchange molecular dynamics and the all-atom explicit-solvent model, we studied the equilibrium binding of Aβ monomers to a zwitterionic dimyristoylphosphatidylcholine (DMPC) bilayer coincubated with calcium ions. Using our previous replica-exchange molecular dynami...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Lockhart, Christopher, Klimov, Dmitri K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2015
Pynciau:
Proteins and Nucleic Acids
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390832/
https://ncbi.nlm.nih.gov/pubmed/25863071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.03.001
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