ロード中...
Molecular Dynamics Simulations of Ibuprofen Binding to Aβ Peptides
Using replica exchange molecular dynamics simulations and the implicit solvent model we probed binding of ibuprofen to Aβ(10–40) monomers and amyloid fibrils. We found that the concave (CV) fibril edge has significantly higher binding affinity for ibuprofen than the convex edge. Furthermore, binding...
保存先:
| 主要な著者: | , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2009
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756381/ https://ncbi.nlm.nih.gov/pubmed/19804739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.032 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|