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Mapping Conformational Ensembles of Aβ Oligomers in Molecular Dynamics Simulations
Although the oligomers formed by Aβ peptides appear to be the primary cytotoxic species in Alzheimer's disease, detailed information about their structures appears to be lacking. In this article, we use exhaustive replica exchange molecular dynamics and an implicit solvent united-atom model to...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Biophysical Society
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941018/ https://ncbi.nlm.nih.gov/pubmed/20858441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.008 |
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