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Mapping Conformational Ensembles of Aβ Oligomers in Molecular Dynamics Simulations
Although the oligomers formed by Aβ peptides appear to be the primary cytotoxic species in Alzheimer's disease, detailed information about their structures appears to be lacking. In this article, we use exhaustive replica exchange molecular dynamics and an implicit solvent united-atom model to...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Biophysical Society
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941018/ https://ncbi.nlm.nih.gov/pubmed/20858441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.008 |
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