Wordt geladen...
Molecular Dynamics Simulations of Anti-Aggregation Effect of Ibuprofen
Using implicit solvent molecular dynamics and replica exchange simulations, we study the impact of ibuprofen on the growth of wild-type Aβ fibrils. We show that binding of ibuprofen to Aβ destabilizes the interactions between incoming peptides and the fibril. As a result, ibuprofen interference modi...
Bewaard in:
| Hoofdauteurs: | , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Biophysical Society
2010
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877328/ https://ncbi.nlm.nih.gov/pubmed/20513411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.031 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|