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Binding of non-steroidal anti-inflammatory drugs to Aβ fibril
Non-steroidal anti-inflammatory drugs are considered as potential therapeutic agents against Alzheimer’s disease. Using REMD and atomistic implicit solvent model we studied the mechanisms of binding of naproxen and ibuprofen to the Aβ fibril derived from solid-state NMR measurements. The binding tem...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058518/ https://ncbi.nlm.nih.gov/pubmed/20635343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22804 |
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