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Globular state in the oligomers formed by Aβ peptides
Replica exchange molecular dynamics and implicit solvent model are used to study two oligomeric species of Aβ peptides, dimer and tetramer, which are typically observed in in vitro experiments. Based on the analysis of free energy landscapes, density distributions, and chain flexibility, we propose...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Institute of Physics
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896418/ https://ncbi.nlm.nih.gov/pubmed/20550420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3447894 |
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