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Does amino acid sequence determine the properties of Aβ dimer?
The effect of random reshuffling of amino acids on the properties of dimers formed by Aβ peptides is studied using replica exchange molecular dynamics and united atom implicit solvent model. We show that thermodynamics of dimer assembly and the dimer globule-like state are not affected by sequence p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Institute of Physics
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155579/ https://ncbi.nlm.nih.gov/pubmed/21787025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3610427 |
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