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Lymphocytes with Aberrant Expression of Fas or Fas-ligand Attenuate Immune Bone Marrow Failure in a Mouse Model

Bone marrow (BM) and lymphocyte samples from aplastic anemia patients show up-regulated Fas and Fas-ligand (FasL) expression respectively, supporting a relationship between immune-mediated BM destruction and the Fas apoptotic pathway. Mice with spontaneous lymphoproliferation (lpr) and generalized l...

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Autors principals: Omokaro, Stephanie O., Desierto, Marie J., Eckhaus, Michael A., Ellison, Felicia M., Chen, Jichun, Young, Neal S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513944/
https://ncbi.nlm.nih.gov/pubmed/19265119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801430
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